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“What’s in the egg to have that power?” said Jose Cibelli, MSU professor of physiology and animal science. “Some of those genes are responsible for the magic trick that the egg has. This paper takes a peek at what genes are in the egg waiting to make these changes,” he added. Combined with sperm, the egg divides and organises cells to ultimately create a human being. Combined with technology, the unfertilised egg might be coaxed to produce other specific cells, including stem cells, which can be directed to grow into new tissue. This potential could be used to combat diseases. Cibelli said his team’s mission is to grow stem cells without using fertilised embryos, which can be controversial. This work used only unfertilised human eggs that were obtained from women seeking fertility treatment at a clinic in Santiago, Chile. Women at the clinic must be reproductively healthy, no older than 35, and the cause of infertility must lie within the man. This presented the availability of exceptionally healthy eggs, Cibelli said. All the donors granted informed consent for their surplus eggs to be used for this research.
—ANI
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In the Proceedings of the National Academy of Sciences recently, scientists reported that they had identified genes unique to the human egg. The identification opened the way to understanding these genes’ functions, which may lead to solving problems from infertility to degenerative diseases.