New gene may halt wheat epidemic

Los Angeles, November 17

Researchers have identified a gene that can help fight a new devastating strain of a fungal disease that is now at the door of the Punjab region — the breadbasket of Asia.

The gene enables resistance to a strain of stem rust, a fungal disease that is hampering wheat production throughout Africa and Asia and threatening food security worldwide.

(Follow The Tribune on Facebook; and Twitter @thetribunechd)

The finding by researchers at the University of California, Davis, will help breeders more quickly develop varieties that can fend off the deadly pathogens and halt a worldwide wheat epidemic.

Wheat and stem rust have been in an evolutionary arms race for more than 10,000 years, researchers said.

In the 1950s, a major epidemic of the disease spread through North America and destroyed up to 40 per cent of the wheat crop, the world’s second most important grain next to rice. Since then, scientists have developed rust-resistant varieties to boost wheat’s immunity to stem rust. However, the pathogens are making a comeback.

A new strain of the stem rust — called Ug99 after it was discovered in Uganda in 1999 — is spreading throughout the region. 

About 90 per cent of the wheat varieties grown worldwide are susceptible to Ug99, researchers said.

“Ug99 has expanded to most of the wheat-growing regions in Africa and has crossed the Red Sea to Yemen and Iran,” said Jorge Dubcovsky, a professor at University of California, Davis. “Ug99 is now at the door of the Punjab region and identification and deployment of effective resistance genes are critical to mitigate this threat.”

The team identified three  resistance forms of Sr13, a gene from pasta wheat that is effective against Ug99 and another group of virulent stem-rust strains from Yemen and Ethiopia. In 2013, Dubcovsky and fellow researchers discovered another gene called Sr35 that also provides resistance to Ug99. 

To develop better varieties, breeders cross plants with desired traits and select the best offspring over multiple generations. Once stem-rust resistant genes have been identified, breeders can use molecular markers (specific regions of DNA) to select the genes at the seed or seedling stage. This accelerates the crop-improvement process.

These molecular markers allow breeders to pyramid multiple stem-rust-resistant genes in the same plant to extend the durability of resistance. — PTI