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Daily Quiz- 234

GK Bank
Cerebrospinal fluid (CSF) for Brain-Eating Amoeba, Naegleri fowleri or N. fowleri RT-PCR test. It's an amoeba that can cause a serious central nervous system infection

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1. Which of the following statements about ingestion (drinking) of Naegleria-contaminated water is correct?
A) Drinking contaminated water will almost always cause Primary Amoebic Meningoencephalitis.
B) Ingestion does not lead to Primary Amoebic Meningoencephalitis because nasal entry is required.
C) Drinking causes transmission via the digestive tract to the brain.
D) All drinking water sources are sterilized against Naegleria by municipal systems automatically.
2. Survival from Primary Amoebic Meningoencephalitis is most likely when:
A) Treatment starts late after coma sets in
B) Early aggressive diagnosis and combination therapy is instituted promptly
C) Only home remedies are used
D) No medical care is given
3. The primary diagnostic challenge in Primary Amoebic Meningoencephalitis is:
A) Pathognomonic early signs are abundant making screening easy
B) Early symptoms mimic common meningitis, leading to delayed diagnosis
C) Easy detection by routine urine tests
D) It can be diagnosed using a pregnancy test
4. Which of the following is a correct public-health recommendation for small village ponds to reduce Naegleria risk?
A) Encourage children to dive frequently to build resistance
B) Improve community awareness, restrict swimming in warm stagnant waters, and consider engineering interventions for water circulation/chlorination where feasible
C) Fill ponds with seawater
D) Close all fresh water sources permanently
5. For exam-focused revision, which of the following is the best quick fact set for Naegleria fowleri?
A) Bacteria — ingestion — low fatality
B) Free-living amoeba — nasal entry — >95% fatality — Amphotericin B Miltefosine used
C) Virus — airborne — easily treatable with antivirals
D) Fungus — skin entry — causes mild rash

Answers Quiz 233 (September 27)

1. B
Explanation: Prevention includes avoiding warm freshwater, nose clips, and ensuring pool chlorination.
2. B
Explanation: PAM typically has 2-7 days incubation, followed by rapid neurological deterioration.
3. B
Explanation: Management emphasizes early aggressive therapy (Amphotericin B, miltefosine) and supportive measures like reducing intracranial pressure.
4. B
Explanation: Warming freshwater makes habitats more suitable for the amoeba, raising risk (climate-linked factor).
5. B
Explanation: Many Kerala cases have involved children swimming/diving in warm ponds or rivers.
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