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Daily Quiz- 170

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Q1. Which of the following is NOT a typical symptom of Hungry Bone Syndrome?
A. Tetany
B. Numbness and tingling
C. Bradycardia due to hypercalcemia
D. Muscle cramps
Q2. Long-standing elevation of PTH before surgery causes:
A. Osteopetrosis
B. Osteitis fibrosa cystica
C. Rickets
D. Osteomalacia due to vitamin C deficiency
Q3. What is the best strategy to prevent Hungry Bone Syndrome in a high-risk patient undergoing parathyroidectomy?
A. High-dose corticosteroids
B. Preoperative calcium and vitamin D supplementation
C. Calcitonin infusion
D. Bisphosphonates immediately after surgery
Q4. Which vitamin D analogue is preferred in the management of HBS?
A. Ergocalciferol
B. Cholecalciferol
C. Calcitriol
D. Alfacalcidol
Q5. Which of the following distinguishes Hungry Bone Syndrome from post-surgical hypoparathyroidism?
A. Elevated alkaline phosphatase in HBS
B. Lower PTH levels in HBS
C. Absence of calcium deficiency in HBS
D. High serum phosphate levels in HBS

Answers Quiz 169 (July 25)

1. B
Explanation: HBS typically occurs after parathyroidectomy in patients with severe hyperparathyroidism, due to the abrupt drop in circulating PTH and consequent calcium uptake by bones.
2. C
Explanation: After parathyroidectomy, demineralised bones rapidly take up calcium, phosphates and magnesium, leading to a sharp decline in serum calcium levels — the hallmark of HBS.
3. D
Explanation: Alkaline phosphatase (ALP) is elevated due to high osteoblastic activity during bone healing and remineralization post-surgery. Serum calcium, phosphate, and magnesium are low.
4. C
Explanation: Chronic kidney disease (CKD) leads to secondary hyperparathyroidism, where PTH levels are chronically elevated. After surgery, these patients are high-risk for HBS due to bone hunger.
5. C
Explanation: Post-parathyroidectomy, calcium shifts into the bones due to the absence of PTH, which previously inhibited this uptake, resulting in hypocalcaemia.
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