Single alcohol dose can 'alter' brain cells : The Tribune India

Single alcohol dose can 'alter' brain cells

Single alcohol dose can 'alter' brain cells

Photo for representation only.

Berlin, September 15

Even a single exposure to alcohol can permanently change the shape of nerve cells and lead to addiction, according to a study conducted in animals.

Neurons or nerve cells are the fundamental units of the brain and nervous system responsible for receiving sensory input from the external world. Researchers found that alcohol affects the structure of the synapses as well as the dynamics of the mitochondria, the cell’s powerhouses.

Also read: Teens who binge drink more likely to drive while intoxicated later in life: Study

Young people face higher health risks from alcohol than older adults: Lancet study

Synapses are the points of contact between neurons, where information is passed from one neuron to the next.

The study, published in the journal Proceedings of the National Academy of Sciences, used the genetic model system of the fruit fly.

It shows that alterations in the migration of mitochondria in the synapses lessen the rewarding effect of alcohol, researchers said.

These findings imply that even a single drinking incident might lay the foundation for alcohol addiction, they said. A majority of studies have focused on the consequences of chronic alcohol drinking on the hippocampus, our brain’s control centre.

“We set out to discover ethanol-dependent molecular changes. These, in turn, provide the basis for permanent cellular changes following a single acute ethanol intoxication,” said Henrike Scholz from the University of Cologne in Germany. “The effects of a single alcohol administration were examined at the molecular, cellular, and behavioural levels,” Scholz said. Researchers used fruit flies and mouse models to find ethanol-induced alterations in two areas — mitochondrial dynamics and the balance between synapses in neurons. — PTI 

Can lead to addiction

We set out to discover ethanol-dependent molecular changes. These, in turn, provide the basis for permanent cellular changes following a single acute ethanol intoxication. — Henrike Scholz, University of Cologne in Germany

Tribune Shorts


Top News

PM Modi to launch 5G services in India today

PM Narendra Modi launches 5G services

Capable of supporting ultra-high-speed Internet, the fifth g...

The 5G makeover: What it means for new as well as existing subscribers

The 5G makeover: What it means for new as well as existing subscribers

As the govt rolls out the revolutionary 5G service, a look a...

India abstains, Russia vetoes UNSC resolution on Moscow's ‘illegal referenda' on Ukraine

India again abstains from anti-Russia UN Security Council resolution

India’s PM has unequivocally conveyed this (dialogue) in his...

Accused who killed factory worker during loot bid at Ludhiana dies by suicide in CIA lock-up

Accused who killed factory worker during loot bid at Ludhiana 'dies by suicide' in CIA lock-up

On September 28, police had nabbed Jatinder Chhotu (29) and ...

Punjab and Haryana High Court allows student's appeal in varsity student's gang-rape case

Punjab and Haryana High Court allows student's appeal in university student's gang-rape case

The verdict is pronounced in the open court by the Division ...


Cities

View All